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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T63875 | Bosutinib hydrate | PF-5208763 hydrate,PF-05208763 hydrate,SKI-606 hydrate | Bcr-Abl , Src |
Bosutinib hydrate (SKI-606 hydrate) is an orally active and potent dual kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of Philadelphia Chromosome Positive Chronic Granulocytic Leukemia. | |||
T10583 | Bosutinib D8 | SKI-606 D8 | Bcr-Abl , Src |
Bosutinib D8 is a deuterium-labeled Bosutinib. Bosutinib (SKI-606) is a dual Src/Abl inhibitor (IC50s: 1.2 nM/1 nM). | |||
T0152 | Bosutinib | SKI-606 | Bcr-Abl , Src , Autophagy |
Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases. |